Kengo Nagashima



Brief description

This web application is an implementation of sample size determination method for Simon's two stage designs (Simon, 1989). This app is implemented in JavaScript, and it does not collect any information from user input. This app is licensed under GPLv3, because the "nTwoStageDesign" function in this app is a modification and translation from the "ph2simon" function in the clinfun package.

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References

  1. Simon R. Optimal two-stage designs for phase II clinical trials. Controlled Clinical Trials 1989; 10(1): 1–10.

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